Wound Infections Research Area Initiatives Support Combat Trauma-Related Infection Evidence-Based Management and Wartime Preparedness


May 5, 2025

One of the key initiatives of the Wound Infections Research Area is to develop evidence-based clinical practice guidelines (CPGs) to prevent and treat combat trauma infections. Another vital focus is to enhance wartime preparedness for potential future conflicts.

Currently, the Wound Infections Research Area team is working on creating technical recommendations to enhance the next-generation Infectious Disease Module of the Joint Trama System Department of Defense Trauma Registry. The recommendations include improving interoperability to ensure better data sharing and collaboration. Additionally, they are developing scientific and regulatory frameworks for Wartime Specimen and Isolate Repositories, which will be crucial for future conflict scenarios.

The team is collaborating with Dr. Scott Evans, Chair of the Department of Biostatistics and Bioinformatics at the Milken Institute SPH, and his team at the Biostatistics Center. Together, they are designing 'ready-to-use' clinical trial protocols that can be activated during future conflicts. These protocols will focus on assessing strategies for preventing combat trauma-related infections and evaluating the effectiveness of various treatment approaches, all aimed at improving outcomes for wounded warriors.